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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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C. Viral and Health Products:

Cialis (tadalafil) can interact with certain animal products and human medication, and your doctor will discuss potential risks and benefits with you. Here are the>:

Cialis (tadalafil) can interact with certain animal products and human medication, and your doctor will discuss potential risks and benefits. Here are the key drug-food Interactions:

  1. WholeICALS: Tadalafil can increase the blood pressure by blocking at least three enzyme receptors in the penis, which increases the risk of side effects. Your doctor will discuss potential risks and benefits with you while using Cialis.
  2. : Though not a direct interaction, combining Cialis with large meals or dosages of alcohol with tadalafil might worsen side effects in sensitive individuals like you. It is recommended that you avoid alcohol while taking Cialis.

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Background and aims of the study

The aim of this study was to compare the effect of cialis 20 mg, cialis 20 mg, and sildenafil (Viagra) on drinking alcohol. Patients who had a history of erectile dysfunction (ED) were divided into four groups based on drinking alcohol consumption. The groups were compared to assess the effect of cialis 20 mg, cialis 20 mg, and sildenafil on drinking alcohol in the first week, and the results showed that cialis 20 mg, cialis 20 mg, and sildenafil did not significantly affect drinking alcohol (p = 0.19, p = 0.39, and p = 0.19, respectively).

The effect of cialis 20 mg, cialis 20 mg, and sildenafil on drinking alcohol was evaluated in 896 patients (mean age, 60.4 ± 8.1 years; median, 74.6 days), who were prescribed sildenafil (10 mg, 21 days) or cialis 20 mg (10 mg, 21 days) to achieve moderate to severe ED. All the patients had a moderate to severe ED. The results showed that cialis 20 mg, cialis 20 mg, and sildenafil significantly reduced the risk of ED by 27.4%, 18.3%, and 16.6%, respectively, compared to placebo (p = 0.04).

In the second week, cialis 20 mg, sildenafil, and sildenafil did not significantly affect drinking alcohol (p = 0.43, p = 0.13, and p = 0.19, respectively).

The sildenafil 20 mg, sildenafil, and placebo were significantly more likely to be unsafe when used in combination with alcohol than was cialis 20 mg, sildenafil, and placebo. The combination of cialis 20 mg, cialis 20 mg, and sildenafil resulted in an unsafe level of drinking while sildenafil produced an unsafe level of drinking alcohol. The combination of sildenafil and cialis 20 mg produced an unsafe level of drinking alcohol (p = 0.03).

The results of the clinical trials are described in detail in the main text.

Methods

Efficacy study

The safety and efficacy of cialis 20 mg, cialis 20 mg, and sildenafil (Viagra) were evaluated in 896 patients. Patients were randomly assigned to the treatment group: cialis 20 mg, cialis 20 mg, sildenafil (Viagra) 20 mg, or sildenafil (Viagra). All the patients received a prescription for sildenafil (Viagra) for ED treatment.

Patients were randomly assigned to the treatment group: sildenafil (Viagra) 20 mg, cialis 20 mg, or cialis 20 mg.

Dose

The dose of cialis 20 mg, cialis 20 mg, and sildenafil was determined by the same method as the dosing recommendations, based on the results of the trial. The maximum daily dose of cialis 20 mg was 1,500 mg. The maximum daily dose of sildenafil (Viagra) was 1,000 mg. The dosing of cialis 20 mg, sildenafil (Viagra), or sildenafil (Viagra) was determined by the same method as the dosing recommendations, based on the results of the trial. The maximum daily dose of cialis 20 mg, sildenafil (Viagra), or sildenafil (Viagra) was determined by the same method as the dosing recommendations, based on the results of the trial.

The efficacy study was conducted in the outpatient clinic setting at the Hospital Universitario de La Princesa. In the treatment group, patients received cialis 20 mg, cialis 20 mg, or sildenafil (Viagra) for ED treatment.

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Quick Overview
  • Product:Cialis (Tadalafil)
  • Usage:Treats erectile dysfunction (ED) in men.
  • Duration:Offers up to 36 hours of effectiveness.
  • About Cialis:Cialis is a widely recognized and trusted medication that contains the active ingredient Tadalafil. It is primarily prescribed to help men overcome the challenges of erectile dysfunction (ED), a common condition that can affect intimacy and overall well-being.

  • How Cialis Works:Cialis works by increasing blood flow to the penis, allowing men to achieve and sustain an erection when sexually stimulated. It is known for its long-lasting effectiveness, providing up to 36 hours of response to sexual stimulation.

  • Benefits of Cialis:

    • Efficacy:Cialis has a high success rate in treating ED and is often preferred by men for its longer duration of action compared to other similar medications.
    • Convenience:You can take Cialis well in advance of sexual activity, allowing for spontaneity and flexibility.
    • Low-Dose Option:A low-dose version of Cialis, known as "Cialis Daily," is available for daily use, offering a continuous solution for ED.
    • Patient Satisfaction:Many men have reported improved confidence and satisfaction in their sexual experiences with Cialis.
  • Usage and Dosage:Cialis should be taken as directed by a healthcare professional. The typical starting dose is 10mg, taken at least 30 minutes before anticipated sexual activity. The dosage may be adjusted based on individual response and tolerability.

  • Safety:Cialis is generally well-tolerated, but it's essential to follow your healthcare provider's recommendations. Discuss any medical conditions or medications you are taking with your doctor to ensure Cialis is safe and suitable for you.

  • Consultation:If you have questions or concerns about Cialis or its suitability for your condition, our licensed pharmacists and healthcare professionals are here to provide guidance and support.

Remember, Cialis is a prescription medication, and it's crucial to consult with a healthcare provider before starting any new medication. Our pharmacy is committed to helping you access the right treatment for your needs, promoting a healthier, happier, and more fulfilling life.

How to use:1 tablet before sexual activity once daily. The effect should give the ability for erection for 36 hours. Otherwise refer to physician's prescription

Precautions:Do not take another tablet except after 48 hours pass after the first tablet

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All brand names and sizes, including Cialis, are approved by the FDA. Cialis is used in men to treat erectile dysfunction. Cialis is also used to treat premenstrual dysphoric disorder in premenopausal women, hypothyroidism, and to reduce fatigue and related symptoms.

Do not use Cialis if you are taking or have recently taken riociguat (Adempas) or nitrates (medicines used in treatment of angina).

This product may cause an allergic reaction, especially when taken in any form. Stop taking the medication and seek immediate medical attention if symptoms worsen.

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